Ice Recrystallization Inhibitors
Articles
2026 | Ice Recrystallization Inhibitors | Articles
Very cold but still too warm; functional characterization of transient warming events in stem cell grafts
Authors: Pineault N, McGregor C, Saleem AM, Ghannouchi L, Morton L, Li M, Ben RN
Published: Cytotherapy; 2026 (Accepted 13 November 2025; published 2026)
2025 | Ice Recrystallization Inhibitors | Articles
Impact of nucleation temperature and hydroxyethyl starch on ice crystal growth: Implications for cell viability during extreme temperature fluctuations.
Authors: William N, Rahman A, Acker JP
Published: Journal of Thermal Biology
2024 | Ice Recrystallization Inhibitors | Articles
Exposure of cryopreserved red cell concentrates to real-world transient warming events has a negligible impact on quality.
Authors: Osmani R, Ehsani-Moghaddam B, Kurach J, Clarke G, Brandon-Coatham M, Acker JP, Olafson C, Turner TR, Phan C, Yazdanbakhsh M
Published: Transfusion
2024 | Ice Recrystallization Inhibitors | Articles
Ice recrystallization inhibitors enable efficient cryopreservation of induced pluripotent stem cells: A functional and transcriptomic analysis
Authors: Del Sol A, Mathieson W, Mommaerts K, Schwamborn JC, Okawa S, Acker JP, Schmitt M, Betsou F, Kofanova O, Turner TR, Ben RN
Published: Stem Cell Research
2023 | Ice Recrystallization Inhibitors | Articles
Engineered Compounds to Control Ice Nucleation and Recrystallization
Authors: William N, Mangan S, Acker JP, Ben R
Published: Annual Review of Biomedical Engineering
2023 | Ice Recrystallization Inhibitors | Articles
Improved cryopreservation of human induced pluripotent stem cell (iPSC) and iPSC derived neurons using ice-recrystallization inhibitors.
Authors: Sandhu J, Tauskela J S, lasmar S, Ben R, Huang J, Jezierski A, Chopra K, Baumann E, Aylsworth A, Hewitt M
Published: Stem Cells
2023 | Ice Recrystallization Inhibitors | Articles
Probing the Mechanism of Action of Small-Molecule Ice Recrystallization Inhibitors Using Proton Nuclear Magnetic Resonance Relaxation.
Authors: McMunn L, D’Costa AS, Bordenave N, Ben R
Published: The Journal of Physical Chemistry Letters
2023 | Ice Recrystallization Inhibitors | Articles
Taking lessons from nature to improve cell therapy cryopreservation
Authors: William N, Coatham M, and Acker JP
Published: Cell and Gene Therapy Insights
2022 | Ice Recrystallization Inhibitors | Articles
First Report of Successful Laser Warming for Frozen Gonadal Tissues and Oocytes in the Domestic Cat Model
Authors: Comizzoli P, Rowlison T, Nagashima J, Acker JP, Ben R, Daly J, Hagedorn M
Published: Biopreservation and Biobanking
2021 | Ice Recrystallization Inhibitors | Articles
Investigating the Solubility and Activity of a Novel Class of Ice Recrystallization Inhibitors
Authors: Ampaw AA, Newell K, Ben RN
Published: Processes
2020 | Ice Recrystallization Inhibitors | Articles
Characterizing the ability of an ice recrystallization inhibitor to improve platelet cryopreservation.
Authors: Waters L, Ben R, Acker JP, Padula MP, Marks DC, Johnson L
Published: Cryobiology
2020 | Ice Recrystallization Inhibitors | Articles
Control of ice recrystallization in liver tissues using small molecule carbohydrate derivatives.
Authors: William N, Acker JP
Published: Cryobiology
2020 | Ice Recrystallization Inhibitors | Articles
Cryoprotectant-dependent control of intracellular ice recrystallization in hepatocytes using small molecule carbohydrate inhibitors.
Authors: William N, Acker JP
Published: Cryobiology
2020 | Ice Recrystallization Inhibitors | Articles
Inhibition of ice recrystallization during cryopreservation of cord blood grafts improves platelet engraftment.
Authors: Jahan S, Adam MK, Manesia JK, Doxtator E, Ben RN, Pineault N
Published: Transfusion
2020 | Ice Recrystallization Inhibitors | Articles
The efficacy of ice recrystallization inhibitors in rat lung cryopreservation using a low-cost technique for ex vivo subnormothermic lung perfusion
Authors: Lautner L, Himmata S, Acker JP, Nagendran J
Published: Cryobiology
2020 | Ice Recrystallization Inhibitors | Articles
Transient loss in membrane integrity following intracellular ice formation in dimethyl sulfoxide-treated hepatocyte and endothelial cell monolayers.
Authors: William N, Acker JP
Published: Cryobiology
2019 | Ice Recrystallization Inhibitors | Articles
Modulating intracellular ice growth with cell permeating small molecule ice recrystallization inhibitors.
Authors: Poisson JS, Acker JP, Briard JG, Meyer JE, Ben RN
Published: Langmuir
2017 | Ice Recrystallization Inhibitors | Articles
Hydroxyethyl starch supplemented with ice recrystallization inhibitors greatly improves cryopreservation of human red blood cells.
Authors: Poisson J, Briard J, Turner TR, Acker JP, Ben R
Published: BioProcessing Journal
2016 | Ice Recrystallization Inhibitors | Articles
O-Aryl-glycoside ice recrystallization inhibitors as novel cryo-protectants – A structure-function study.
Authors: Inada T, Acker JP, Capicciotti C, Ben R, Mancini R, Turner TR, Koyama T, Alteen M, Doshi M
Published: ACS Omega
2016 | Ice Recrystallization Inhibitors | Articles
QSAR accelerated discovery of potent ice recrystallization inhibitors.
Authors: Briard JG, Fernandez M, De Luna P, Woo TK, Ben RN
Published: Scientific Reports
2016 | Ice Recrystallization Inhibitors | Articles
Small molecule ice recrystallization inhibitors mitigate cellular damage during freezing, transient warming and thawing.
Authors: Briard JG, Poisson JS, Turner TR, Acker JP, Ben RN
Published: Scientific Reports
2016 | Ice Recrystallization Inhibitors | Articles
Small-molecule ice recrystallization inhibitors improve the post-thaw function of hematopoietic stem and progenitor cells.
Authors: Briard JG, Jahan S, Chandran P, Allan D, Pineault N, Ben RN
Published: ACS Omega
2015 | Ice Recrystallization Inhibitors | Articles
Inhibiting gas hydrate formation using small molecule ice recrystallization inhibitors.
Authors: Tonelli D, Capicciotti CJ, Doshi M, Ben RN
Published: RSC Advances
2015 | Ice Recrystallization Inhibitors | Articles
Quantitative analysis of the efficacy and potency of novel small molecule ice recrystallization inhibitors.
Authors: Abraham S, Keillor K, Capicciotti CJ, Perley-Robertson E, Keillor JW, Ben RN
Published: Crystal Growth & Design
2015 | Ice Recrystallization Inhibitors | Articles
Small ice recrystallization inhibitors enable freezing of human red blood cells with reduced glycerol concentrations.
Authors: Capicciotti CJ, Tchir JDR, Turner T, Mancini RS, Acker JP, Ben RN
Published: Scientific Reports
2014 | Ice Recrystallization Inhibitors | Articles
Designing ice recrystallization inhibitors: From antifreeze (glyco)proteins to small molecules.
Authors: Balcerzak AK, Capicciotti CJ, Briard JG, Ben RN
Published: RSC Advances
2010 | Ice Recrystallization Inhibitors | Articles
Assessing the ability of a short-fluorinated antifreeze glycopeptide and a fluorinated carbohydrate derivative to inhibit ice recrystallization.
Authors: Chaytor JL, Ben RN
Published: Bioorganic & Medicinal Chemistry Letters